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Dr rajendra kumar kanojia

University

Title: Incidence of osteomalacia in osteoporotic fractures around hip joint: IN ASIAN SUBCONTINENT

Biography

Biography: Dr rajendra kumar kanojia

Abstract

Osteoporosis is a skeletal disease characterized by low bone mass and micro architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture (WHO 1994). Osteoporosis is an important health issue around the world that estimates to affect more than 200 million people energy year worldwide.

In India around 50 million population of Indian are either osteoporotic or have low bone mineral density (BMD).

Among Indian woman age 30-60 years, BMD at all skeletal sites were much lower than values from other countries reported, with a high incidence of osteopenia (52%) and osteoporosis (29%), may be due to inadequate nutrition.

Material & Method

This is a prospective study conducted at PGIMER, both in OPD and ATC ward, among all patients admitted with the history of fracture involving neck of femur and intertrochantric, excluding metastatic hip fractures conservatively treated fractures,  patients in which biopsy could not be taken and those with secondary osteoporosis.

Calcium profile, serum cretinine, urea, bilirubin, AST and ALT levels were measured. Hb ALC, IPTH, Vit. D were analysed.

During peri-operative procedure, bone biopsy specimen measuring 0.5-1 cm size was sampled and sent from histological assessments.

Results

Post fragility fracture in seven patients (15.6%) was previous history of fragility fracture (due to minor trauma) and rest 38 patients (84.4%) had no history of such type of fracture. Corrected calcium level 20 patients (44.4%) were showed abnormal calcium level below 8.8 mg/dl and rest 25 patients (55.6%) were showed normal value.

Ca xp product value 19 patients (42/2%) showed values below 27 mg/dl and rest 26 patients (57.8%) showed normal values.

Serum Vit. D level normal level is 11.1 – 42.9 mg/ml  22 patients (48.9%) showed values below  11.1 mg/ml. and rest 23 patients (51.1%) showed normal serum vit D level.

Conclusion – Vit. D deficiency is highly prevelant among fragility hip fractures patients in north Indian population.